Envision this possible future clinical scenario: a breast cancer patient and her physicians are deciding on the best possible ...

Trastuzumab deruxtecan plus pertuzumab demonstrated statistically and clinically significant improvement in progression-free ...

Abstract:        Obesity, a growing global issue, has been closely associated with an increased risk of various cancers, especially breast cancer. El ...

Triple-negative breast cancer (TNBC) is one of the most aggressive and difficult-to-treat forms of breast cancer. Unlike ...

B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME).

Envision this possible future clinical scenario: a breast cancer patient and her physicians are deciding on the best possible ...

Trastuzumab deruxtecan plus pertuzumab outperformed standard-of-care therapy as first-line treatment for HER2-positive ...

Adding Enhertu to Perjeta improved time without cancer growth versus standard care in advanced HER2-positive breast cancer, ...

"Proteogenomics provides a powerful approach to refine biomarker discovery and reveal critical mechanisms underlying drug resistance or novel vulnerabilities in HER2+ breast cancer," said co ...

HER2+ breast cancer usually undergo pre-operative therapy with multi-agent chemotherapy in combination with anti-HER2 antibodies, followed by surgery.

ACCURATE determination of HER-2 status in breast cancer is essential for guiding targeted therapy and improving clinical ...