The results of gene therapy for hemophilia B contrast with those of factor replacement therapies, where lifelong infusions ...

It was found that those with severe hemophilia B have less than 1% of normal factor IX activity, often experiencing spontaneous bleeding that can cause joint damage or life-threatening events.

A gene transfer approach to treating the bleeding disorder hemophilia B remains safe and effective long-term, as scientists ...

Hemophilia is a genetic disorder in which a person’s blood does not clot normally. This can lead to spontaneous or excessive bleeding, according to the Centers for Disease Control and Prevention ...

Learn how clotting factor therapy, gene therapy, and non-factor treatments are improving hemophilia prognosis and life expectancy.

This spontaneous mutation pattern explains why hemophilia A can appear unexpectedly in families with no known bleeding disorders. Genetic testing now allows precise identification of the specific ...

For centuries, hemophilia was a dangerous genetic disorder with no treatment. Children with hemophilia often didn't make it to adulthood, since a bump or fall could cause massive internal bleeding.

Hemophilia C is an autosomal inherited form of the disease. It affects biological males and females equally because the genetic defect that causes this type of hemophilia isn’t related to sex ...

Managed Healthcare Executive gives C-suite executives in health plans and provider organizations news and strategies for ...

“For the rare genetic blood-clotting disease hemophilia—typically present at birth—the excessive bleeding endured by children with this disease can lead to progressive disability with pain ...

Of the hundreds of genetic diseases linked to the X chromosome, Duchenne is among the more common, along with certain forms of hemophilia. Other so-called X-linked disorders include Fabry disease ...

In a 13-year follow-up by St. Jude Children’s Research Hospital and University College London published in The New England ...