Oncogene - Blocking anaplerotic entry of glutamine into the TCA cycle sensitizes K-Ras mutant cancer cells to cytotoxic drugs Skip to main content Thank you for visiting nature.com.

They found that glutamine was required to maintain the TCA cycle as well as for asparagine synthesis. Asparagine is one of the most common amino acids and plays an important role in glycosylation ...

Aging, which is associated with various pathologies such atherosclerosis and cancer, is characterized by an accumulation of senescent cells. Cellular senescence blocks cell proliferation, but it ...

Cancer cells feed on sugar-free diet Date: January 10, 2012 Source: Johns Hopkins Medicine Summary: Cancer cells have been long known to have a “sweet tooth,” using vast amounts of glucose for ...