Pain is more than a physical signal — it also carries emotional weight that shapes our response and memory of discomfort.

Does using Ozempic cause brain fog? It depends on who you ask. This article takes a closer look at what’s going on with ...

The Semaglutide peptide has emerged as a compelling subject in biochemical and physiological research due to its potential ...

Researchers at the Headache Center of the University of Naples "Federico II" gave the glucagon-like peptide-1 (GLP-1 ... pharmacologically targetable pathway." Mild gastrointestinal side effects ...

In response to extracellular ligands, G protein-coupled receptors (GPCRs) undergo conformational changes that induce coupling to intracellular effectors such as heterotrimeric G proteins that trigger ...

Furthermore, the peptide's potential to modulate signaling networks suggests its utility in exploring the interplay between metabolic and signaling pathways. Implications in Metabolic Research One of ...

Furthermore, glucagon signaling was identified as the top-ranked signaling pathway affected in the cardiomyocytes associated with HFpEF. Treatment with a glucagon receptor antagonist significantly ...

Of note, PAX6 replenishment increased the protein expression of those signaling components as well as the insulin‐ and incretin‐induced signaling pathways (Fig 5E–H). Beta cell identity was also ...

We also found that glucagon activates p38α through the protein Epac2 signaling in hepatocytes. This signaling could be another area to investigate for a possible therapeutic intervention.

Therefore, inhibiting this phosphorylation could be a therapeutic strategy. We also found that glucagon activates p38α through the protein Epac2 signaling in hepatocytes. This signaling could be ...

How Brains Send a Signal That It’s Time to Vomit In a study of mice, researchers worked out a neural pathway that could help researchers alleviate nausea symptoms from chemotherapy drugs.