Breast cancers at all stages are defined by the structure of their genomes, researchers find. Targeting these processes early is likely to offer unexpected therapeutic avenues.

In the first half of 2025, Ozempic developer Novo Nordisk in Bagsværd, Denmark, expects results from a second phase III trial ...

In this regard, chemical inducers of proximity (CIPs) offer a promising approach to precisely manipulate protein–protein interactions in live cells and in vivo. In this study, we introduce pMandi, a ...

Lipidated analogues of glucagon-like peptide 1 (GLP-1 ... This work provides a systematic study of the solubility, structure, oligomerization, and long-term stability of five different lipidated ...

Researchers have profiled the molecular structure and features of a key part of the deadly Nipah virus. Experiments in cells showe how changes in the viral polymerase -- a protein involved in ...

"Obesity is gradually eroding human health," and the global prevalence of obesity (BMI > 30) is predicted to reach 25 % by 2035, affecting nearly 1.9 billion people. The demand for medications to ...

Once in the pancreas, those immune cells release cytokines-tiny chemical messengers-that instruct pancreatic cells to produce the hormone glucagon. The increase in glucagon then signals the liver ...

Traditionally, blood sugar regulation has been attributed to the hormones insulin and glucagon, both produced ... the gut connected to the brain release chemical signals that bind to immune ...