Weight-loss drugs like Ozempic and Wegovy are used by more than 15 million adults in the U.S., or 4.5% of the population.

Semaglutide, a synthetic analog of glucagon-like peptide-1 (GLP-1), has garnered attention for its intriguing properties and potential implications in various r ...

Over the past decade, the global pharmaceutical industry has witnessed a transformation in the treatment landscape for ...

In the current structure, domains B and C have moved closer ... The superposition also brings the ADP moiety of the NAD + molecule in the active site into overlap, confirming that NAD + binding ...

Despite its intrinsically subjective nature, attempts to quantify the similarity of compounds have a long history in chemical informatics and drug discovery. Many computational methods employ ...

Phenol red–free variable amino acid RPMI cell culture medium was obtained from Life Technology. The sex-steroid hormone used was DHT (Sigma Chemical Co) because it cannot be aromatized to estrogenic ...