Multiple gastrointestinal stromal tumors typically occur in familial form associated with KIT receptor tyrosine kinase or platelet-derived growth factor receptor-alpha (PDGFRA) germline mutations ...

Gastrointestinal stromal tumors (GISTs): definition, occurrence, pathology, differential diagnosis and molecular genetics. Polish journal of pathology : official journal of the Polish Society of ...

Background Gastrointestinal stromal tumor (GIST) ... 2 Department of Pathology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China *Correspondence ...

Gastrointestinal stromal tumors are a group of mesenchymal neoplasms that arise from precursors of the connective-tissue cells of the gastrointestinal tract. 1 They occur predominantly in middle ...

Gastrointestinal Stromal Tumors: Study May Result In More Targeted Drugs Date: November 24, ... Ph.D., vice chairman for research and professor of pathology and OHSU Knight Cancer Institute member.

New York, USA, April 15, 2025 (GLOBE NEWSWIRE) -- Gastrointestinal Stromal Tumor Market to Grow Rapidly During the Study Period (2020–2034) Owing to the Launch of Emerging Therapies | DelveInsight .

Next opening: 2027-2028 Number of positions: 1 Length: 1 year. This ACGME-accredited fellowship provides robust training in disorders of the luminal GI tract, pancreas and hepatic pathology (medical ...

Gastrointestinal stromal tumor is the most common neoplasm of mesenchymal origin, 1 with an annual incidence of approximately 6,000 cases in the United States. Most cases are driven by oncogenic KIT 2 ...

More information: Feifei Xie et al, Genomic and transcriptomic landscape of human gastrointestinal stromal tumors, Nature Communications (2024). DOI: 10.1038/s41467-024-53821-1. Provided by BGI ...

Most advanced gastrointestinal stromal tumors (GISTs) start with cancer-causing cell changes, or mutations, in specific genes. Changes in proteins called KIT and PDGFRA most commonly cause this ...

In summary, radical surgery is the treatment of choice for operable GISTs. Very low- and low-risk diseases can be treated with surgery alone. Lymph node metastasis is rare in GIST patients and may ...