Happy to share that my first post-doc work on Pd-catalyzed alkyl amination of olefins via radical polar crossover to construct biologically important gamma-lactams is now published in @angewchem ...

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TOPLINE: For patients with beta-lactam allergy undergoing orthopedic surgery, prioritizing cefazolin as the preferred antibiotic for the prevention of surgical site infections (SSIs) did not lead ...

LYTENAVA™ is the first and only approved ophthalmic formulation of bevacizumab for the treatment of wet AMD in the European Union (EU) and United Kingdom (UK)2.8 million injections of repackaged ...

Scynexis has resumed a trial of Brexafemme, triggering a $10M milestone payment from GSK and another $20 million due in six months, Scynexis says.

The FDA has given the green light to Exblifep, based on long-established beta-lactam antibiotic cefepime and a new extended-spectrum beta-lactamase inhibitor (BLI) ...

AbbVie has claimed FDA approval for Emblaveo, a new antibiotic product to treat complicated intra-abdominal infections (cIAI), including those caused by Gram-negative bacteria that represent a ...

Consider the beta-lactams, such as penicillin -- while these are the drug class of choice for sensitive strains of S pneumoniae, no beta-lactam can provide coverage for organisms such as M ...

Terrestrial gamma-ray flashes usually appear in fleeting bursts. They have been linked to energetic electrons racing through electric fields high above ground. Most gamma-ray sources are thought to ...

Limited treatment options exist to combat infections caused by multidrug-resistant (MDR) Gram-negative bacteria possessing broad-spectrum β-lactamases. The design of novel β-lactamase inhibitors is of ...