First, GABA is initially excitatory. Second, GABA synapses are formed before glutamatergic ones. Third, the excitatory actions of GABA generate a primitive pattern of activity, which helps to ...

Surprisingly, GABA is not be involved in initial synapse formation, however, but rather in pruning them back, a process analogous to speed dating. Quite early in its development, the mammalian ...

The neurotransmitters GABA and glycine, on the other hand, transmit an inhibitory message, telling the subsequent cell not to fire. At excitatory synapses, Prof. Takahashi's group has previously ...

The team treated cultured hippocampal neurons from one-day-old rat pups with leptin and found that it increased the presence of synapses that signal with the neurotransmitter gamma aminobutyric acid ...

He said neuroscience researchers have long hypothesized that these synapses might form because of a release of GABA and the corresponding sensing activity between two neurons in proximity.

that GABA neurons in the VTA may have a direct connection with the synapses of local DA neurons. The putative mechanism underlying this relationship was highlighted by light-activation of GABA ...

Yale researchers used light to probe the actions of the neurotransmitter GABA on single synapses along the branches of a neuron. The work, appearing in the May 10 issue of the journal Science, ...

Over the past decade, several studies have focused on two proteins that are related to synapses mediated by GABA, the most important inhibitory neurotransmitter in mammals. Npas4, the first of the ...

Weiner's work focuses on what is called the GABA synapse which he says contributes to many of alcohol's behavioral and cognitive effects, especially intoxication, dependence and withdrawal.

That much they had anticipated. The unexpected observation was that GABA proved not to be involved in the initial formation of these tentative or "test" synapses, but rather in the essential ...

The neurotransmitters GABA and glycine, on the other hand, transmit an inhibitory message, telling the subsequent cell not to fire. At excitatory synapses, Prof. Takahashi's group has previously ...