The model consists of a specific number of excitatory and inhibitory neurons that are connected through AMPA, NMDA, and GABA synapses. The study used a short-term recall to simulate working memory ...

These functional changes were underlain by vigorous nanoscale redistribution of GABA A Rs within the synapse, including an increase in PSD size and a reduction in local enrichment of receptors with ...

[Nayak et al] GABA-driven signaling at the neural synapses is modulated by GABA receptor proteins that interact with GABA released from the preceding neurons in the circuit. Excess GABA released ...

Inhibitory neurons use the neurotransmitter gamma-aminobutyric acid (GABA) to decrease activity in the nervous system. At inhibitory synapses, these neurons release GABA molecules into the ...

Benzodiazepines work by binding GABA-A receptors; however ... In TSPO knockout mice, diazepam did not alter synapses or cognition, hinting that the drug may work through TSPO. In support of this, ...

Microglia, the primary brain macrophages, regulate a plethora of processes that impact the organization of neural circuits, including synapse pruning. Whether microglia are generic effectors of ...

This study analyzes the internal organization of mixed inhibitory spinal cord synapses using dSTORM and reveals the existence of trans‐synaptic nanocolumns containing GlyRs and GABA A Rs that are ...

The team treated cultured hippocampal neurons from one-day-old rat pups with leptin and found that it increased the presence of synapses that signal with the neurotransmitter gamma aminobutyric acid ...

Nearly half of all synapses of the brain express some kind of GABA receptor. GABAA receptors are widely but differentially distributed within the CNS and they can be activated by several GABA ...

Communication at these synapses happens when one neuron fires off packets of GABA molecules that are then quickly detected by proteins called GABA type A (GABAA) receptors on neighboring neurons.