Over the last decade, substantial evidence has accumulated to show that endurance exercise training elevates muscle GLUT4 content and insulin-stimulated glucose uptake in both healthy [17, 20, 21 ...

Finally, GLUT4 was visualized by an alkaline phosphatase-labeled antibody and quantified on a phosphoimager (STORM; Molecular Dynamics, Sunnyvale, CA). Data are means ± SE.

PHILADELPHIA, June 17, 2025 /PRNewswire/ -- Integral Molecular, the industry leader in discovering antibodies against membrane proteins, is pleased to announce that it has out-licensed a panel of ...

BioWorld - Saturday, June 21, 2025 Breaking News: Trump administration impacts continue to roil the life sciences sector See today's BioWorld Science Home » Stimulating glucose uptake by GLUT4 to ...

A study of thousands of people finds that neural connections in the brain start to break down quickly around age 44 but that ketone supplements could help slow that brain aging, the research hints.

Moving your muscles helps keep your blood sugar in check. Is walking or squatting more effective for improving blood sugar?

When you perform squats, your muscles produce lactate, which signals muscle cells to bring GLUT4 transporters to their surface. These transporters pull glucose from the bloodstream into the muscles, ...

Using cutting-edge CRISPR technology, Brunet and her team conducted a comprehensive genetic screen to identify genes that, when inhibited, could reactivate dormant neural stem cells in aged mice.

Knocking out the GLUT4 gene increased new neuron production in older mice. The study suggests possible treatments through glucose control or dietary changes. Source: Stanford Most neurons in the human ...

The formation of insulin-sensitive GLUT4-containing compartments involves direct secretion that bypasses the Golgi apparatus and uses the dedicated clathrin isoform CHC22. This study defines two key ...

The GLUT4 transporter plays a key role in insulin-induced glucose uptake, which is impaired in insulin resistance. The objective of the present study was to investigate the tissue content and the ...