Genomic GR-binding site sequence affects GR activity. Previous studies relied on transiently transfected reporters to show that GBS composition can modulate GR activity 11,13.To determine if GBS ...

GBS spacer affects GR occupancy, activity and structure. We sought to determine the degree of sequence variability among endogenous GBSs to estimate the potential for DNA sequences to be unique ...

The scientists used a technique known as multilocus sequence typing (MLST) to examine similarities and differences between the genes of the GBS isolates. This was the first study to apply the ...