CHICAGO -- Neoadjuvant nivolumab (Opdivo) plus chemotherapy significantly improved overall survival (OS) compared with ...

FRACTION-RCC: Innovative, high-throughput assessment of nivolumab + ipilimumab for treatment-refractory advanced renal cell carcinoma (aRCC). Biomarker analyses from the phase III CheckMate 214 trial ...

Morbid sequelae include smooth muscle cell (SMC) hyperplasia and restenosis due to vascular neointima formation. Methods and Results In this study, we examined the inhibitory effects of a concentrated ...

Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Bio-Sensing and Chemometrics, College of Chemistry and Chemical Engineering, Aptamer Engineering Center of Hunan Province, ...

Department of Veterinary Medicine, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 106, Taiwan, Division of Environmental Health and Occupational Medicine, National Health Research ...

In the present study, we review approaches and studies that have shed some light on cardiomyocyte cell cycle regulation. For reference, an initial description of cardiomyogenic induction and ...

Cells respond to the perception of DNA damage by arresting cell-cycle progression and attempting ... consequently produce visibly bigger foci. Checkpoint enforcement is a direct consequence ...

Many of the components of this DNA replication apparatus associate with other cellular factors as components of multiprotein complexes, which act cooperatively in networks to regulate cell cycle ...

The high-risk group was enriched in tumor progression pathways (like epithelial-mesenchymal transition, cell cycle checkpoints), exhibited low expression of immune checkpoint genes (BTLA, CD47), and ...

Non-small cell lung cancer (NSCLC) is the predominant histological type, accounting for 85% of all lung cancer cases. In recent years, immune checkpoint inhibitors (ICIs) have revolutionized NSCLC ...