These fundamental findings offer a novel mechanism by which rubrerythrin tubules encapsulate encapsulin to prevent oxidative stress in Pyrococcus furiosus. However, there are a few reasonable concerns ...

Researchers from the Göttingen Cluster of Excellence Multiscale Bioimaging (MBExC) have uncovered the 3D structure of the ...

Researchers from the Göttingen Cluster of Excellence Multiscale Bioimaging (MBExC) have uncovered the 3D structure of the membrane proteins myoferlin and dysferlin using high-resolution cryo-electron ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...

Rather than being like battery chargers, mitochondria are more like the motherboard of the cell.

It’s a protein ... a key regulator of mitochondrial fusion, the team discovered. Without it, then, the network of fused-together mitochondria inside our cells collapses, making them less ...

In Molecular Cell Prof. Li Dong's group from the ... pathway in which aberrant phase separation of a fusion protein drives ER membrane remodeling and nuclear signaling. The findings not only ...

Since it was known that women with obesity have elevated levels of Mitch, the researchers postulated that this protein is vital not only for mitochondrial fusion but also for fat cell ...

Ebola viruses (EBOVs) assemble into filamentous virions, whose shape and stability are determined by the matrix viral protein 40 (VP40). Virus entry into host cells occurs via membrane fusion in late ...

The FDA has granted a fast track designation to IBI363 for the treatment of unresectable locally advanced or metastatic melanoma that has progressed following at least 1 line of systemic therapy, ...

which can then be reused elsewhere in the cell. Autophagy fusion is mediated by three members of the SNARE protein family; syntaxin17 and SNAP29 are initially found in the cytosol before being ...

Membrane fusion is considered the first step in the entry of enveloped viruses into the host cell. Several targeted strategies have been implemented to block viral entry by limiting the fusion protein ...