Objective: The present study aimed to evaluate the effects of NAC as a treatment for 5-fluorouracil-induced oral mucositis in hamsters. Methods: The animals were divided into two groups: therapeutic ...

5-fluorouracil (5-FU) is among the mostly administrated chemotherapeutic agents for a wide variety of neoplasms. Non-coding RNAs have a central impact on the determination of the response of patients ...

To better understand the drug’s mechanism, Demehri’s lab created ... on a filed patent for the use of calcipotriol plus 5-fluorouracil for the treatment of precancerous skin lesions (PCT ...

An unexpected mechanism Clinicians use 5-fluorouracil (5-FU) as a first-line drug for colon, rectal, and pancreatic cancers. It's usually given in combination with oxaliplatin or irinotecan, which ...

Usually, 5-fluorouracil is given in combination with ... Textbooks implicate the DNA effects of the drug as the mechanism in all cancer types, but our data shows that RNA damage is what's really ...

Usually, 5-fluorouracil is given in combination with ... "Textbooks implicate the DNA effects of the drug as the mechanism in all cancer types, but our data shows that RNA damage is what's really ...

Usually, 5-fluorouracil is given in combination with ... "Textbooks implicate the DNA effects of the drug as the mechanism in all cancer types, but our data shows that RNA damage is what's really ...

How does topical fluorouracil work (mechanism of action)? Topical fluorouracil interferes with the ability of cells to grow and divide. The medicine causes cell death, especially among cells that ...

Predoctoral Fellow of the National Institutes of Health, U. S. Public Health Service (EF-9085). This work was supported by a grant (E-1181) from the National Institutes of Health, U. S. Public Health ...