The development of novel adjuvants signifies a pivotal advancement in immunotherapy, introducing innovative mechanisms to enhance and precisely modulate immune responses. Traditional adjuvants have ...

Italy AIM To evaluate the efficacy of topical 5-fluorouracil (5-FU) alone, without concurrent surgery or radiotherapy, for the treatment of conjunctival squamous cell carcinoma. METHODS Eight patients ...

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5-fluorouracil is a thymine analog. Via an unknown mechanism it acts selectively on AK dysplastic cells, causing apoptosis and destruction. Another advantage of this medication is that it allows ...

The Food and Drug Administration (FDA) is announcing the establishment of a docket to solicit public comment for information on dihydropyrimidine dehydrogenase (DPD) deficiency and the use of ...

Objective: The present study aimed to evaluate the effects of NAC as a treatment for 5-fluorouracil-induced oral mucositis in hamsters. Methods: The animals were divided into two groups: therapeutic ...

Objective: The present study aimed to evaluate the effects of NAC as a treatment for 5-fluorouracil-induced oral mucositis in hamsters. Methods: The animals were divided into two groups: therapeutic ...

the mechanisms comprising miR-519d-3p’s role in CRC drug resistance have not been fully understood. Therefore, the present study aimed to investigate the biological function of miR-519d-3p in the ...

Hepatocellular carcinoma (HCC) is the most common primary malignant tumor of the liver and is usually caused by chronic liver disease or cirrhosis (1). Liver cancer is the leading cause of ...

Collaboration with UMass Chan Medical School confirmed FMR1-217 as well as an RNA-targeted mechanism to restore functional FMRP protein to develop potential treatments for FXS QurAlis ...