Fat isn’t just a guilty pleasure — it’s cancer’s secret weapon. New research from UT Southwestern Medical Center is shedding light on why this is the case.In a study published this month in the ...

By establishing an iron overload-induced hepatic ferroptosis model, scientists from Japan have identified iFerroptosis—an ...

By establishing an iron overload-induced hepatic ferroptosis model, scientists from Japan have identified iFerroptosis-an ...

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Scientists at the USC Leonard Davis School of Gerontology have discovered a key connection between high levels of iron in the ...

USC researchers have uncovered a hidden driver behind the early and severe onset of Alzheimer's in people with Down syndrome: ...

The study reveals a significant relationship between elevated iron levels in the brain and greater cellular damage in individuals with both Down syndrome and Alzheimer’s disease.

However, the origin of this lipid peroxidation that causes ferroptosis has remained a topic of debate," explains Professor Ken-ichi Yamada of Kyushu University's Faculty of Pharmaceutical Sciences ...

The team discovered that peroxidation of lysosomes plays a key role in the execution of ferroptosis-mediated cell death. Additionally, they found that lysosomal lipid peroxidation causes the membrane ...

Ursini, F. and Maiorino, M. (2020) Lipid Peroxidation and Ferroptosis The Role of GSH and Gpx4. Free Radical Biology and Medicine, 152, 175-185.