By establishing an iron overload-induced hepatic ferroptosis model, scientists from Japan have identified iFerroptosis—an ...

The study, "Down syndrome with Alzheimer's disease brains have increased iron and associated lipid peroxidation consistent ...

By establishing an iron overload-induced hepatic ferroptosis model, scientists from Japan have identified iFerroptosis-an ...

This damage is known as lipid peroxidation and it's a key feature of ferroptosis. Once lipid peroxidation starts, it quickly spreads to the cell's outer layer, damaging the main barrier and ...

USC researchers have uncovered a hidden driver behind the early and severe onset of Alzheimer's in people with Down syndrome: ...

The study reveals a significant relationship between elevated iron levels in the brain and greater cellular damage in individuals with both Down syndrome and Alzheimer’s disease.

Scientists at the USC Leonard Davis School of Gerontology have discovered a key connection between high levels of iron in the ...

These findings reveal that Nrf2 alleviates colistin-induced nephrotoxicity by suppressing ferroptosis through the GPX4-mediated lipid peroxidation inhibition and mitochondrial protection, highlighting ...