In 2 separate studies, ezetimibe/simvastatin lowered C-reactive protein, LDL cholesterol, and apolipoprotein B levels more than simvastatin or atorvastatin alone.

CRP levels were also further reduced with the combination therapy, a reduction of 46% with rosuvastatin and ezetimibe vs a 28.6% reduction with rosuvastatin alone.

Compared with placebo or either agent alone, a combination of bempedoic acid and ezetimibe lowered LDL to a greater degree, researchers reported.The researchers also wrote that the combination was ...

Statin therapy reduces low-density lipoprotein (LDL) cholesterol levels and the risk of cardiovascular events, but whether the addition of ezetimibe, a nonstatin drug that reduces intestinal choles ...

The results suggest that this approach, using biomarkers like C-reactive protein (CRP) and high-sensitivity cardiac troponin T (hs-cTnT), could identify higher-risk patients in the post-ACS setting.

In patients with familial hypercholesterolemia, combined therapy with ezetimibe and simvastatin did not result in a significant difference in changes in intima–media thickness, as compared with ...

Adding ezetimibe (Zetia) therapy to statins early after a heart attack improved outcomes, Swedish national records suggested. With statins almost universally used in this setting, people who also ...

LONDON, England—Adding the cholesterol-absorption inhibitor ezetimibe to simvastatin and usual care is safe and can improve outcomes substantially, especially among diabetics, according to results of ...

Achievement of Dual LDL-C (<70 mg/dL) and hs-CRP (<2 mg/L) Goals More Frequent with Addition of Ezetimibe and Associated with Better Outcomes in IMPROVE-IT ...

For patients with hypercholesterolemia, simvastatin is superior to ezetimibe for producing lymphocyte-suppression and systemic anti-inflammatory and endothelial protective effects.

Adding ezetimibe to atorvastatin significantly boosted the attainment of lipid targets as specified by both Canadian and European guidelines in elderly patients aged ...