The selective estrogen-receptor modulators (SERMs ... premenopausal women with breast cancer. As the molecular mechanisms of the action of SERMs become more completely understood, rational ...

Researchers discovered a mechanism by which estrogen can trigger fast neuronal ... This classical mode of action as a nuclear receptor takes minutes to hours. "Estrogen also can change the firing ...

It is well known that, upon stimulation by estrogen, ER-alpha enters the cell nucleus where it mediates the transcription of genes. This classical mode of action as a nuclear receptor takes ...

An open label phase I study of ABR-215050 in patients with prostate cancer refractory to hormone therapy and with rising PSA for determination of MTD and long-term tolerability and safety No ...

"We are now investigating the biochemical mechanisms that mediate the estrogen-dependent inhibition of caspase-3 activity in osteoblasts and whether other pharmacological or nutritional agents might ...

In this article, explore different hormone types, functions, and mechanisms of action, as well as hormonal imbalance consequences and research on potential treatments. What Are Hormones and Where Are ...

OBJECTIVE: Estrogen has been implicated in feeding behavior and adiposity. This study was undertaken to elucidate the mechanism underlying the anti-obesity and anorectic action of estrogen and the ...

Potential mechanisms of estrogen-driven carcinogenesis include prostatic estrogen receptor-mediated events, epigenetic changes, genotoxicity, hyperprolactinemia and chronic inflammation.

He and his group believe that studying the hormone-regulated reproduction have a better chance of elucidating the molecular action of juvenile ... flies use the same mechanism in mediating ...

Each class of SERMs (orange symbols) has a slightly different shape, although all will bind to the estrogen receptor. When it binds to an estrogen, antiestrogen, or SERM, the estrogen receptor ...

The study appeared in Science Advances. It is well known that, upon stimulation by estrogen, ER-alpha enters the cell nucleus where it mediates the transcription of genes. This classical mode of ...

Potential mechanisms of estrogen-driven carcinogenesis include prostatic estrogen receptor-mediated events, epigenetic changes, genotoxicity, hyperprolactinemia and chronic inflammation.