Blacksmith Medicines, Inc. (Blacksmith), a leading biopharma dedicated to discovering and developing medicines targeting metalloenzymes, announced today that it will present preclinical data on its ...

Obesity is a significant global health challenge, linked to an increased risk of conditions like diabetes, heart disease, and ...

Pulmonary fibrosis (PF) is a chronic lung disease characterized by the replacement of normal lung tissue by scar tissue, resulting in worsening lung function and impaired gas exchange. Autotaxin (ATX) ...

A recent study by a team from Chiba University has demonstrated a promising approach for fighting antibiotic resistance by identifying a compound, V-161, that inhibits a sodium-pumping enzyme critical ...

Under the direction of Dr. Guru Subramanian Guru Murthy at the Medical College of Wisconsin Cancer Center, the trial ( NCT06502145) will evaluate the safety, tolerability, and recommended Phase II ...

However, a recent study from Johns Hopkins University offers new hope. Researchers found that an experimental drug, ...

Keloids are fibrotic scars that extend beyond the boundaries of the original wound, often causing physical disfigurement and ...

The study's findings are crucial in the rapidly emerging field of developing disease-modifying therapies that target microglia.

A collision happens. Someone is hurt, a head injury, a concussion. Just as the first responders arrive to help the person, inside the brain, another "crew" of responders is busy clearing debris and ...

In an exciting advancement for dermatological science, researchers have uncovered the pivotal role of vitamin D and the enzyme CYP24A1 in the development of keloid scars—an elusive and challenging ...

Glycolysis is a central metabolic pathway by which cells obtain energy from sugar. Cancer cells in particular have long been ...

Microglia, the brain’s immune cells, play vital roles in clearing toxins and maintaining neuronal health but can also ...