Enhertu is a HER2-directed antibody and topoisomerase ... Study participants with HR-positive, HER2-low or HER2-ultralow metastatic breast cancer who disease had progressed on endocrine therapy ...

Median progression-free survival (PFS) was 13.2 months with ENHERTU compared to 8.1 months with chemotherapy. Results were consistent in patients with HER2 low expression and HER2 ultralow expression.

In February, AstraZeneca and Daiichi Sankyo teased the results of their pivotal trial of Enhertu in HER2-low breast cancer, and, at ASCO, they finally revealed the data – with the numbers every ...

The median duration of response (DOR) was 14.3 months in the ENHERTU arm (95% CI: 12.5-15.9) versus 8.6 months in the chemotherapy arm (95% CI: 6.9-11.5) as assessed by BICR. In the HER2 low ...

The FDA will speed up their review of Enhertu for HR-positive, HER2-low/ultralow advanced breast cancer that cannot be removed via surgery. The Food and Drug Administration (FDA) granted a ...

which demonstrated that Enhertu reduced the risk of disease progression or death by 37% in patients with HER2-low or HER2-ultralow metastatic breast cancer. The FDA has granted Priority Review to ...

“In DESTINY-Breast06, ENHERTU outperformed chemotherapy, providing progression-free survival of more than one year for patients with HR positive, HER2 low or HER2 ultralow metastatic breast ...

Researchers at ASCO's annual meeting also discussed the importance of repeat biopsies to assess HER2 status after first-line ...

In the ENHERTU arm, the majority of ILD or pneumonitis events were low grade (grade 1 [n=7 ... which represent the first time a HER2 directed medicine has demonstrated a survival benefit in ...

The majority of ILD or pneumonitis events were low grade (grade 1 [n=17 ... “Bringing ENHERTU earlier in the treatment of HER2 positive metastatic breast cancer may represent an important ...