During a Case-Based Roundtable® event, Joshua K. Sabari, MD, continued discussion of key outcomes from the MARIPOSA trial and toxicity management in patients with EGFR-mutated non–small cell lung ...

The impact of ORes on the expression levels of key proteins in the EGFR/PI3K/AKT/GPX4 signalling axis was assessed using Western blot analysis. Cells were lysed in RIPA buffer (Beyotime, P0013K, China ...

1Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire. 2Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire.

More information: Bassel Alsaed et al, Intratumor heterogeneity of EGFR expression mediates targeted therapy resistance and formation of drug tolerant microenvironment, Nature Communications (2025).

“It’s time to get back to our roots around free expression on Facebook and Instagram. I started building social media to give people a voice,” Zuckerberg said. “The recent elections also ...

1 Rybrevant is a bispecific antibody that targets EGFR and MET with immune cell-directing activity, whereas Lazcluze is a kinase inhibitor. The therapy is indicated for the treatment of adult patients ...

In addition, it was found that HDCA could inhibit the EREG/EGFR signaling pathway by activating the expression of FXR, and then inhibit the proliferation of CRC. The present study still has some ...

Epidermal growth factor receptor (EGFR) is expressed in 50% of NSCLCs, and its expression is correlated with poor prognosis. These two factors make EGFR and its family members prime candidates for ...