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The epidermal growth factor receptor (EGFR) plays an important role in the pathogenesis of many tumors. To analyze the expression of EGFR and activated EGFR in well-differentiated neuroendocrine ...
High epidermal growth factor receptor (EGFR) expression was a good predictor of which lung cancer patients would survive longer when cetuximab (Erbitux) was added to first-line chemotherapy ...
We advance the hypothesis that a molecular switch, responsible for downregulating EGFR expression by androgens in the normal prostate, is either lost or modified in PCa. Several studies have ...
Significant benefit in locoregional tumor control from continuous hyperfractionated accelerated radiotherapy was seen in patients with HNSCC with high EGFR expression (2P = .010) but not in those with ...
To clarify the role of EGFR in the outcome of non–small-cell lung cancer, we evaluated the expression of EGFR protein, the number of copies of EGFR, and mutation status of the gene in a subgroup ...
1d
News-Medical.Net on MSNStudy aims to demystify the immune toxicity triggered by osimertinib-ICI co-treatmentNon-small cell lung cancer (NSCLC) accounts for the majority of lung cancer cases and remains a leading cause of cancer ...
12d
News-Medical.Net on MSNNew insights reveal EGFR as a target in KRAS-mutated colon cancerKRAS mutations are among the most common genetic alterations in cancer and are considered particularly difficult to treat.
In a recent study, researchers have uncovered the biological trigger behind the dangerous immune-related adverse events ...
Autophosphorylation of EGFR was measured with antibody against phosphotyrosine at position 1068, and standardized to total protein expression, shown with the use of antibody against EGFR (working ...
9d
AZoLifeSciences on MSNStudy Identifies SMARCB1 and MEOX2 Genes as Growth Regulators of Lung CancersA Cancer Gene Therapy study reveals that MEOX2 promotes lung cancer progression while SMARCB1 acts as a tumor suppressor, ...
High epidermal growth factor receptor (EGFR) expression was a good predictor of which lung cancer patients would survive longer when cetuximab (Erbitux) was added to first-line chemotherapy ...
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