Researchers have pinpointed the precise pathway in the brain that suppresses pain in times of threatening situations.

Its lead asset, Plinabulin, is in late-stage clinical development as an anti-cancer agent in NSCLC and a range of cancer indications. Plinabulin’s novel mechanism of action as a dendritic cell ...

Other Recently Approved Agents (eg, gemcitabine and docetaxel) Mechanism of Action: These are chemotherapy agents. Gemcitabine works by inhibiting DNA synthesis in rapidly dividing cancer cells, while ...

In this GEN webinar, our expert speaker Dave Lahr, PhD, Senior Director of Bioinformatics at Foghorn Therapeutics, will describe how chromatin mapping assays such as CUT&RUN, ATAC-seq, and ...

Further, studying the mechanism of action helps in determining the optimal conditions for the use of preservatives, such as concentration and exposure time, ...

Figure 1: Mechanism of action of Bacillus Calmette-Guérin (BCG) and sequential Gemcitabine/Docetaxel (Gem/Doce) for the treatment of localized non-muscle-invasive bladder cancer Figure 2: Any-Grade ...

LEO Pharma A/S, a global leader in medical dermatology, today announced positive results from the Phase 2a Mechanism of Action (MoA) trial, which assessed the mechanistic impact of investigational ...

New mechanism of action kills cancer cells Date: August 14, 2024 Source: Ruhr-University Bochum Summary: Conventional cancer drugs work by triggering apoptosis, that is programmed cell death, in ...

AEs of special interest (AESIs) corresponding to the immune-mediated mechanism of action of atezolizumab (Data Supplement, Table S5) were observed in 123 patients (66.5%) in the atezolizumab plus ...

Theratechnologies Inc. (“Theratechnologies” or the “Company”) (TSX: TH) (NASDAQ: THTX), a biopharmaceutical company focused on the development and commercialization of innovative therapies, today ...

Conclusions Pyrotinib, trastuzumab, and docetaxel showed superiority by significantly improving progression-free survival ... a more aggressive disease and an unfavourable prognosis.1 2 The ...

The mechanism of action of docetaxel involves the disruption of microtubule dynamics and interfering with cell division. This leads to apoptosis and cell cycle arrest. Docetaxel mainly targets ...