Given the amino-acid sequence or 3D structure of a protein, how much can we predict about its function using just a desktop computer? The recent explosive growth in the volume of sequence data and ...

Feb. 3, 2025 — Biological scientists have uncovered how the dengue virus uses its envelope protein to capture human plasmin from a blood meal to enhance the permeability of the mosquito midgut ...

When Alphabet announced in 2021 that its AlphaFold AI could predict the structure of almost every known protein, it was a major story, not just in the pharma world, but beyond.

The crystal structure of the core domain (N-terminal 30 kDa domain) of cytoskeletal protein 4.1R has been determined and shows a cloverleaf-like architecture. Each lobe of the cloverleaf contains ...

Yuan, W. & Krug, R. M. Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN) ... This paper provides the first structure of an OAS protein.

Researchers at the Max Planck Institute of Biochemistry investigate the structure of these proteins and how they function – from individual molecules through to complex organisms. They make use of the ...

Immunoprecise Antibodies Ltd. has discovered a highly conserved epitope across all four dengue virus serotypes (DENV-1, DENV-2, DENV-3 and DENV-4) using its proprietary Lensai platform powered by its ...

A pivotal target of this approach is the hepatitis B virus (HBV) X protein (HBx), which is a key factor that promotes transcription from cccDNA. However, the HBx structure remains unsolved. Here, we ...

Important factors governing NPs–protein interactions include the size (curvature), surface charge, and surface state of NPs as well as coexisting ions in solvents. In this study, we focused on the ...

Nipah virus (NiV) is a serious hazard to human health since it can cause severe respiratory infections and viral encephalitis with a high fatality rate. Given the lack of a licensed NiV vaccine, there ...