Specific features of the folded-back structure suggest strategies for inhibiting flavivirus entry. Figure 1: Structure of the dimer of dengue E soluble fragment (sE) in the mature virus particle.

The crystal structure ... of the Zika and dengue virus immunocomplexes provides a lead for rational, epitope-focused design of a universal vaccine capable of eliciting potent cross-neutralizing ...

Viruses are tiny agents that can infect a variety of living organisms, including bacteria, plants, and animals. Like other viruses, the dengue virus is a microscopic structure that can only ...

The structure of mature dengue virus particles was determined to a ... as well as part of the N-terminal section of the M proteins, are buried in the outer leaflet of the viral membrane.

The team also identified regions within the Zika virus structure where it differs from other flaviviruses, the family of viruses to which Zika belongs that includes dengue, West Nile ... chief of the ...

dengue fever, West Nile and yellow fever. His research involves studying the structure of viruses and how they interface with the cells of their hosts’ bodies — hence the mapping of the Zika ...