and daratumumab (PDB: 7DHA) target CD38 at non-overlapping epitopes. These two antibody-antigen complexes were determined independently, and their structures do not influence each other. Case 2 : When ...

How cancer patients relying on daratumumab feel physically before starting the therapy can predict how long they will live and how well they will respond to the anti-multiple myeloma (MM ...

A new four-drug combination is highly effective and safe in patients with newly diagnosed multiple myeloma, according to data presented at the annual meeting of the American Society of Clinical ...

Pieter Sonneveld, MD, PhD, professor of hematology and chair of the Erasmus MC Cancer Institute in Rotterdam, Netherlands, discussed the continued use of subcutaneous daratumumab following initial ...

Can you describe the modeling strategy used to predict long-term outcomes for patients receiving frontline quad therapy of daratumumab plus VRd? In the PERSEUS trial for transplant-eligible ...

In August 2012, Janssen Biotech, Inc. and Genmab A/S entered a worldwide agreement, which granted Janssen an exclusive license to develop, manufacture and commercialize daratumumab. Systemic ...

in favor of the benefit-risk profile of single-agent DARZALEX FASPRO (daratumumab and hyaluronidase-fihj) for the treatment of adult patients with high-risk smoldering multiple myeloma (HR-SMM).

Maxine Waters, will block efforts to hold a joint hearing between her committee and the House Agriculture Committee on Monday's newly unveiled market structure discussion draft bill. Under House ...

“And now that we have this structure, perhaps we can find ways to modulate its function.” For example, compounds that target the receptor could alter how natural sugars are sensed by taste ...

Crews in Dauphin County were called to a barn fire Saturday night.The fire was on Bellaire Road near Colebrook Road in Conewago Township. It started around 10:10 p.m. No injuries have been ...