When DNA breaks inside the cell, it can spell disaster, especially if the damage occurs in areas of the genome that are ...

A powerful new discovery reveals that Nup98 a protein once thought to only ferry molecules through the nucleus plays a vital ...

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized ...

The Collection “DNA Replication and Replication Stress” brings together original research articles, critical reviews, and perspectives from scientists with diverse viewpoints and areas of ...

The mammalian liver has an extraordinary regenerative capacity, capable of fully restoring its mass and function after injury ...

Alzheimer's disease is the most common cause of dementia and affects more than a tenth of Americans aged 65 and older. The ...

The mammalian liver has an extraordinary regenerative capacity, capable of fully restoring its mass and function after injury ...

POLG mutations impair mitochondrial DNA replication and cause diverse mitochondrial diseases. Here, the authors show that structural differences in the POLγB subunit between humans and mice ...

A new study in Nature Plants reveals that DNA double-strand break repair (DSBR) pathways help prevent gene transfer from ...