Given its importance, DNA replication is tightly regulated, primarily upon initiation at genomic sites known as origins of replication. A two-pronged structure known as a replication fork forms at ...

the 'wings' and N-termini of RTP do not form intimate contacts with the DNA. This structure provides insight into the molecular basis of polar replication fork arrest based on a model of ...

The replication fork continues for a total of two-thirds of the genome before encountering the O L. This results in the single-stranded DNA in this region to form a stem-loop structure which ...

However, the process of DNA replication intrinsically disrupts nucleosomes ahead of the fork raising the question how chromatin structure is maintained across generations. Nucleosomes are re-assembled ...

When a cell divides to give rise to two daughter cells, the DNA-replicating machinery unfolds the chromatin as it moves along the DNA strands. Once the so-called replication fork (the structure ...

Each time a part of a chromosome unwinds for replication, regions of DNA unzip, forming a structure that looks like a fork in the road. For replication to proceed, the fork must move down the ...

Given its importance, DNA replication is tightly regulated, primarily upon initiation at genomic sites known as origins of replication. A two-pronged structure known as a replication fork forms at ...