Researchers have identified a form of molecular motion that has not previously been observed. When what are known as "guest molecules"—molecules that are accommodated within a host molecule—penetrate ...

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such structure, the G-quadruplex (G4), looks like a knot. These knots can play ...

to show that RAD52 proteins form an unexpected spool-like structure composed of two rings of RAD52, each containing 11 copies of protein, that engages all three arms of the "DNA replication fork ...

Double ring structure protects DNA Spies and Pichierri had previously discovered that RAD52 is important in protecting stalled DNA replication forks. Their work suggested that this new function of ...

A single physiological G4 or iM structure stalls the eukaryotic replisome by inhibiting leading strand synthesis. Helicase‐polymerase uncoupling occurs following replication stalling at G4s. iMs can ...

Each time a part of a chromosome unwinds for replication, regions of DNA unzip forming a structure that looks like a fork in the road. For replication to proceed, the fork must move down the strand of ...

We also obtained a 6.2-Å structure of CMG–ssDNA containing only ... has important biological consequences, discussed below. DNA oligos were synthesized by IDT: (i) The replication fork (41/65-Tamn ...

The nephew of a man killed in New York City 15 years ago has been arrested for his murder after officials obtained DNA evidence on a plastic fork connecting him to the slaying. A grand jury ...

DNA replication. biological process of producing two identical replicas from one original molecule. replication fork. Vector diagram shows how both strands of the DNA helix are unzipped and copied.

DNA replication. biological process of producing two identical replicas from one original molecule. replication fork. Vector diagram shows how both strands of the DNA helix are unzipped and copied.