The interplay of mono- and polyubiquitylation together with sumoylation of PCNA in response to DNA damage provides a glimpse of how replication-fork structure and activity is controlled by a ...

Broken replication forks with single double-stranded ... copy number requires a change in chromosome structure, joining two formerly separated DNA sequences. These junctions give important ...

DNA (deoxyribonucleic acid), the molecular "blueprint" carrying the genetic instructions that influence the growth, ...

The Kostenki 11 site, located near the Don River, just 300 kilometers from Moscow, is one of the most significant Upper ...

To address this possibility, we measured the effect of IBC and BKC on replication fork progression in MCF-7 and BJ cells by using a DNA fiber spreading assay. Briefly, the cells were exposed to one or ...

Researchers at the University of Toronto have invented a new method that uses DNA sequencing to measure metabolites. This ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means ...

Of particular importance, Neandertal DNA also seems to influence the structure and function of the cerebellum. Although most neuroscientists have tended to think of this brain region as ...

Of course, though, testing a child's parentage based on physical features is far too subjective — that's typically where DNA tests come in. Such tests can offer a far more scientific way of ...

It was my own fault that the Man Fork landed on my doorstep. I was talking too big a game at the soft opening of my friend’s Italian restaurant Scampi. I was loose and chatting with pals ...

In his book The Mathematical Universe, mathematician William Dunham wrote of John Venn’s namesake legacy, the Venn diagram, “No one in the long history of mathematics ever became better known ...