Polyploidy, or whole-genome duplication (WGD), is a major mechanism of genome evolution across the tree of life and is ...

Glucose levels influence physiology and adaptation rates under replication stress, yet core adaptive mutations remain ...

Absorption of UV-radiation in nucleotides initiates a number of photophysical and photochemical processes, which may finally cause DNA damage. One major decay channel of photoexcited DNA leads to ...

AlphaGenome scores mutation effects across coding and non-coding DNA, bringing gene insights to the base-pair level.

In a step toward treating mitochondrial diseases, researchers in the Netherlands have successfully edited harmful mutations ...

In a step toward treating mitochondrial diseases, researchers in the Netherlands have successfully edited harmful mutations ...

Preservation of the coding potential of the genome and highly regulated gene expression over the life span of a human are two fundamental requirements of life. These processes require the action of ...