A predictive biophysical model that integrates protein-DNA structures and sequences to accurately determine genomic binding sites and affinities of DNA-binding proteins.

In living organisms today, complex molecules like RNA and DNA are constructed with the help of enzymes. So how did these molecules form before life (and enzymes) existed? Why did some molecules end up ...

In living organisms today, complex molecules like RNA and DNA are constructed with the help of enzymes. So how did these molecules form before life (and enzymes) existed? Why did some molecules end up ...

SMC (structural maintenance of chromosomes) protein complexes are ring-shaped molecular motors essential for genome folding. Despite recent progress, the detailed molecu ...

A Ph.D. graduate student in biomolecular engineering at UC Santa Cruz, with a background in computer science and mathematics, ...

The Siberian flying squirrel (Pteromys volans) is a nocturnal and arboreal rodent that inhabits the boreal taiga forests from ...

All living organisms encode the amino acid sequences of proteins as nucleotide sequences (genetic information) in their ...

Discover what glycan analysis can reveal about protein behavior and how it can be used to boost biologic performance and ...

If a gene is evolutionarily conserved, that shows it must be doing something important. Otherwise, nature would let it go.

Nucleic acids articles from across Nature Portfolio Nucleic acids (DNA or RNA) are polymers of nucleotides – each nucleotide consists of a pentose sugar, a phosphate group and one of the ...