A predictive biophysical model that integrates protein-DNA structures and sequences to accurately determine genomic binding sites and affinities of DNA-binding proteins.

In living organisms today, complex molecules like RNA and DNA are constructed with the help of enzymes. So how did these molecules form before life (and enzymes) existed? Why did some molecules end up ...

In living organisms today, complex molecules like RNA and DNA are constructed with the help of enzymes. So how did these molecules form before life (and enzymes) existed? Why did some molecules end up ...

SMC (structural maintenance of chromosomes) protein complexes are ring-shaped molecular motors essential for genome folding. Despite recent progress, the detailed molecu ...

All living organisms encode the amino acid sequences of proteins as nucleotide sequences (genetic information) in their ...

Ultraviolet (UV) rays from sunlight can cause DNA damage that leads to skin aging and cancer. Fortunately, our bodies have a ...

Scientists have used DNA's self-assembling properties to engineer intricate moiré superlattices at the nanometer ...

Inside each cell of the human body are proteins that control which genes are expressed at the right place and time. However, ...

The increasing incidence of genetic and rare diseases is a major factor driving revenue growth in the Antisense Oligonucleotide (ASO) ...

There's a myth floating around that most of our intelligence is inherited from our mothers, but there are a few good reasons ...

This makes it far easier to perform this type of assembly in real life, because you’d need to generate a much smaller set of custom DNA molecules. These would then be mixed together and, voila, you’d ...