The latest imaging method from the Broad Institute uncovers structural disruptions in the nucleus associated with progeria at ...

Early research shows that editing expanding trinucleotide repeats halts the lengthening process that causes neurological ...

We introduce MADna, a sequence-dependent coarse-grained model of double-stranded DNA (dsDNA), where each nucleotide is described ... we will refer to them as bonds, angles, and dihedrals, respectively ...

Abstract: It has been shown that electropherograms of DNA sequences can be modeled with hidden Markov models. Basecalling ... basecalling in order to estimate the HMM parameters. In this paper, we ...