News

GEN - Genetic Engineering and Biotechnology News1d
Million Species Listing: Basecamp Research Unearths Trove of Sequence Data From Novel Species
BaseData aims to improve AI models in biology by offering a 10-fold expansion of protein diversity compared to all public ...
eLife8d
Distal Gene Expression Governed by Lamins and Nesprins via Chromatin Conformation Change
This study provides useful information on the impact of Lamin A/C knockdown on gene expression using RNA-Seq analysis. In addition, the impact of Lamin A/C knockdown on telomere dynamics is explored ...
C&EN8d
Stabilization by Extra-Helical Thymines of a DNA Duplex with Hoogsteen Base Pairs
Departament d’Enginyeria Química, Universitat Politècnica de Catalunya, E-08028 Barcelona, Spain, Plataforma Automatitzada de Cristallografia, PCB-CSIC, E-08028 Barcelona, Spain, Plate-forme de ...
eLife15d
Synonymous mutations in AAV Rep enhance genome packaging in a library selection
The authors created a useful collection of Rep protein variants with changes that alter the amino acid sequence, but these did not lead to clear improvements in how the virus worked. Instead, their ...
C&EN16d
Crystal Structure of Homo-DNA and Nature's Choice of Pentose over Hexose in the Genetic System
Contribution from the Department of Biochemistry, School of Medicine, Vanderbilt University, Nashville, Tennessee 37232, Department of Chemistry and Biochemistry, Concordia University, Montreal, ...
SciELO28d
19-base pair deletion polymorphism of the dihydrofolate reductase (DHFR) gene: maternal risk of Down syndrome and folate metabolism
This study evaluated the influence of a 19-base pair (bp) deletion polymorphism in intron-1 of the ... and this is responsible for abnormalities in the pattern of deoxyribonucleic acid (DNA) ...