Many people believe that American biologist James Watson and English physicist Francis Crick discovered DNA ... bases now fit together perfectly (i.e., A with T and C with G), with each pair ...

and Asp-56 are situated close enough to contact the phosphate backbone or the unpaired nucleotide base through water-mediated interactions and may contribute to maintaining a unique DNA conformation.

DNA is a blueprint of life ... which places more emphasis on the representation of nucleic-acid bases, the model of Cragnolini et al. elaborates on the nucleotide backbone, which is represented by 5 ...

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized ...

A unique feature of HR is that it repairs the damage to the DNA in a highly accurate way. In eukaryotic cells (those with a ...

Early research shows that editing expanding trinucleotide repeats halts the lengthening process that causes neurological disease.

The authors created a useful collection of Rep protein variants with changes that alter the amino acid sequence, but these did not lead to clear improvements in how the virus worked. Instead, their ...

You may have seen it in the news recently: a baby in Pennsylvania with a rare genetic disorder was healed with a personalized ...

This study provides useful information on the impact of Lamin A/C knockdown on gene expression using RNA-Seq analysis. In addition, the impact of Lamin A/C knockdown on telomere dynamics is explored ...

DNA's double helix has long stood as the symbol of life’s code. But buried within the genome lies a deeper level of complexity. One of the more intriguing discoveries in recent years is the i-motif—a ...