Abstract Summary Pharmacological enhancement of endoplasmic reticulum (ER) proteostasis is an attractive strategy to mitigate pathology linked to etiologically-diverse protein misfolding diseases.

Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...

CRISPR construct to genetically ablate the GABA transporter GAT3 in the mouse visual cortex, with effects on population-level neuronal activity. This work is important, as it sheds light on how GAT3 ...

The global amino acid market is experiencing robust growth driven by rising consumer health awareness, increasing dietary supplement use, demand from ...

Pelicans draft decision labeled 'worst trade, non-Luka division, in at least a decade' by assistant GM What New Orleans did in the first round may be the headline of the 2025 NBA Draft ...

Newsboys members told fans they had been dropped from their label after former bandmate Michael Tait "confessed" to unwanted sexual advances.

The pair of Boston Red Sox pitcher signings, Lucas Giolito and Walker Buehler, were labeled as one of MLB's biggest failures.

Atlanta Braves designated hitter Marcell Ozuna was called a 'best fit' for the New York Yankees and a few other American League contenders.

Zohran Mamdani appears poised to be the Democratic nominee for mayor, where he could face a contested race that will include Eric Adams and perhaps Andrew Cuomo.

New Texas Law Could Change How Food Additives Are Labeled Nationwide By Carole Tanzer Miller HealthDay ReporterTUESDAY, June 24, 2025 (HealthDay News) — Texas has become the first state to ...

Though the listeria recall was upgraded, information remains limited. Here's what we know about the recall, which is active only in NC.