The potential of cyclic peptides in drug discovery has become increasingly apparent in recent years. Their cyclic structure imbues them with enhanced target affinity, metabolic stability and a ...

[4] Amide-to-ester substitution as a stable alternative to N-methylation for increasing membrane permeability in cyclic peptides. Nature Communications (2023). Back to "Proteins and Peptides" ...

A lipophilic extract of an eastern Caribbean collection of Lyngbya majuscula yielded two new halogenated fatty acid amides, grenadamides B (1) and C (2), and two new depsipeptides, itralamides A (3) ...

Reaction of cyclic thioanhydrides with amines affords amides functionalized with thioacids, which can be trapped in situ with electron-deficient azides or, preferably, 2,4-dinitrobenzenesulfonamides.

Niacinamide and vitamin C are more popular than ever. You can combine these vitamins for healthier and brighter skin—here's how. For years, dermatologists have touted the benefits of ...

Partnering with Cyclic Materials helps us take a meaningful step towards enhancing the recovery of already-processed materials and placing them for reuse back into the supply chain.” Lime intends to ...

Anandamide is a cannabinoid that naturally arises in the human body, commonly known as the “bliss molecule” due to its unique ability to induce feelings of joy and fulfillment. This essential ...

If you’re looking for a high-quality palmitoylethanolamide supplement, then Rosmolo’s PEA supplement is an excellent choice. We highly recommend this product for its high dose and superior ...

Consumer Medicine Information (CMI) about Cosamide 50 (bicalutamide) intended for persons living in Australia.

cAMP is a universal second messenger that plays central roles in cardiovascular regulation influencing gene expression, cell morphology, and function. A crucial step toward a better understanding of ...

Similarly, glutathione S-transferase (GST) may act as an amide carrier protein for translocating these HCAAs to the plasma membrane (Macoy et al., 2015). Cinnamoyl tryptamine was found to inhibit ...