Recently, butlers to orange-colored cats got a bit of a shock when reading the news, as headlines began to call out their ...

Patients with vitiligo experience impacts on quality of life, emerging therapies offer promising prospects for more targeted ...

Abstract: Cyclic adenosine 3’,5’-monophosphate (cAMP) is a versatile secondary messenger that communicates with Guanine Nucleotide Exchange Factor (EPAC) to transfer cellular signaling and regulates ...

Using genetic and biochemical assays, we found that Acb2 bound the OptS-synthesized nucleotide, 2′,3′-cyclic adenosine monophosphate (2′,3′-c-di-AMP); however, 2′,3′-c-di-AMP was synthesized ...

Patients are prone to airway contraction when cells lose cyclic adenosine monophosphate. Patients with asthma had higher average serum cAMP levels than patients who did not have asthma.

THE biologic role of cyclic AMP (adenosine 3′,5′-monophosphate), at least as it is understood today, is shown in Figure 1. After release from an endocrine gland, a hormone is transported to ...

The activation of this receptor increases levels of the intracellular signaling molecules, cyclic adenosine monophosphate (cAMP) and inositol triphosphate (IP3). Both cAMP and IP3 eventually ...

dDepartment of Pediatrics, Interdisciplinary Stem Cell Institute, Leonard M. Miller School of Medicine, University of Miami, Miami, FL, 33136, United States eDepartment of Medicine, Interdisciplinary ...

Phosphodiesterase 2 (PDE2) regulates intracellular cyclic adenosine monophosphate and guanosine monophosphate (cAMP/cGMP) levels, which contribute to processes crucial for learning and memory. BI ...