7b00732. Scoring summary of in-cell PKA activation determined using the FRET biosensor and stimulated with permeable cyclic nucleotide analogs, kinase activity of PKA type Iα holoenzymes without and ...

Objective—To investigate whether patients with angina-like chest pain and normal coronary angiograms are more sensitive to adenosine as an inducer of chest pain. Design—Increasing doses of adenosine ...

To address the problematic optimization issue, we propose new joint optimization objectives and a novel Cyclic Differentiable ARchiTecture Search framework, dubbed CDARTS. Considering the structure ...

Discovery of the Interplay Between Length-Dependent Changes in Cardiac Function (Starling’s “Law of the Heart”) and Changing Myocardial Contractility: The “Family of Starling Curves” The interplay ...

Here we ask the fundamental questions about the effect of peptide topology on self-assembly. The study revealed that the self-assembling behaviors of cyclic and linear peptides are significantly ...

Non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common chronic liver disease globally and is currently estimated to affect up to 38% of the global adult population. NAFLD is a ...