The SBMA therapy AJ201 showed good safety, hints of efficacy, and improved physical activity for this SMA type in a trial, ...

Being cut off in traffic, giving a presentation or missing a meal can all trigger a suite of physiological changes that allow ...

thereby restricting access of the drug to a large hydrophobic pocket in which most kinase inhibitors bind (Fig. 1). The authors propose that this first molecular recognition step acts as a ...

kinase chemical probes, allosteric modulators, targeted kinase protein degradation and kinase inhibition for non-oncology indications will be covered, along with views and perspectives on the future ...

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as well as the effect of the supplementation on the creatine kinase (CK) assay measurement. Forty-nine sedentary individuals participated in a double-blind study and were divided into two groups: C ...

Department of Molecular Pharmacology and Biological Chemistry, School of Medicine, Northwestern University, Chicago, Illinois 60611, Biographics Laboratory 3R, CH-4056 Basel, Switzerland, Department ...