Being cut off in traffic, giving a presentation or missing a meal can all trigger a suite of physiological changes that allow ...

Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

We modelled the ability of pathways activated by tyrosine kinase receptors to induce GBM formation in mice with the RCAS/tv-a system, which allows post-natal gene transfer in a cell-type ...

† Department of Biochemistry and Molecular Genetics, and ‡ Center for Pharmaceutical Biotechnology, University of Illinois at Chicago, Chicago, Illinois 60607 ...

(27) Here, we have determined the crystal structure of SPHK1 with 1 ... Fractions containing SPHK1 were pooled and concentrated to 10 mg/mL. Expected molecular weight: 41120.1 Da. Measured molecular ...