The new instrument could make single-molecule measurements accessible ... and our normal confocal microscopes were overbooked,” Gambin says. The microscope costs about $25,000 with top-end ...

It supports various modes of operation: single-molecule localization-based super-resolution for quantitative cellular imaging; single-particle tracking in live cells; DMD-based confocal microscopy; ...

and mounting and operating the devices in a specifically designed holder installed on the inverted microscope of a confocal single-molecule instrument. Figure 2: Cartridge and cartridge holder for ...

Single-molecule localization microscopy (SMLM ... to that possible with conventional confocal microscopy (right). (Image: Florian Schueder, MPI/LMU) PALM utilizes photoactivatable fluorescent proteins ...

“We wanted to democratize single-use molecule measurements to make ... commercial and home-built microscopes. “While the microscope we describe is built for ALEX [alternating laser excitation] ...

Single Molecule Localization Microscopy (SMLM ... in the imaging technique used—FPALM uses traditional confocal fluorescence microscopy, whereas PALM and STORM utilize TIRFM (Total Internal ...

The polarization extension for the LSM upgrade kit permits to access single molecule dynamics such as fluorescence ... The polarization extension is directly mounted to the scan head of the confocal ...