and mounting and operating the devices in a specifically designed holder installed on the inverted microscope of a confocal single-molecule instrument. Figure 2: Cartridge and cartridge holder for ...

It supports various modes of operation: single-molecule localization-based super-resolution for quantitative cellular imaging; single-particle tracking in live cells; DMD-based confocal microscopy; ...

Researchers have succeeded in developing a microscope that offers a resolution better than five nanometers – which is five billionths of a meter. For comparison, the imaging offered by the newly ...

The new instrument could make single-molecule measurements accessible ... and our normal confocal microscopes were overbooked,” Gambin says. The microscope costs about $25,000 with top-end ...

Single-molecule localization microscopy (SMLM ... to that possible with conventional confocal microscopy (right). (Image: Florian Schueder, MPI/LMU) PALM utilizes photoactivatable fluorescent proteins ...

Single Molecule Localization Microscopy (SMLM ... in the imaging technique used—FPALM uses traditional confocal fluorescence microscopy, whereas PALM and STORM utilize TIRFM (Total Internal ...

With dSTORM, a single-molecule localization microscopy ... such as systems that combine confocal laser-scanning microscopy and SMLM. With these systems, imaging data between modalities can ...

“We wanted to democratize single-use molecule measurements to make ... commercial and home-built microscopes. “While the microscope we describe is built for ALEX [alternating laser excitation] ...

The Wolfson Bioimaging Facility is exceptionally well equipped for confocal laser scanning microscopy (CLSM ... They are SMD HyDs for single molecule detection enabling photon counting applications ...

State-of-the-art microscopy is a vital tool in understanding the critical mechanisms of cell growth and division. We provide the latest in live cell imaging technology, enabling scientists at The ...

Researchers have demonstrated a switch, analogous to a transistor, made from a single ... from a molecule in this way. "This technique is similar to the way a photoelectron emission microscope ...