If measured from beginning to end, the DNA in our cells is too long to fit into the cell's nucleus, explaining why it must be ...

Study reveals how cells regulate repair protein production to prevent DNA damage over-repair or under-repair, aiding cell ...

This is the job of chromatin, a complex of proteins that packages and condenses DNA within the cell nucleus. However, in this condensed form, the DNA is unreadable and therefore inactive.

When a cell prepares to divide, its DNA condenses into the discrete rods that constitute the chromosomes’ most iconic form, as can be seen in this time-lapse video of cells with labeled chromosomes.

The islands of condensed DNA around a DNA break move faster than do healthy DNA, yet the mobility of such islands strongly depends on their size.

New imaging tools reveal how within an hour of infection, the virus begins to alter our chromosomes to kick-start its own replication.

This study demonstrated that the scaffold delivery system encapsulating PEI-condensed DNA encoding for BMP-4 was capable of enhancing bone formation and may find applications in other tissue types.

Molecules of DNA get wrapped around histone proteins while being condensed, forming structures called nucleosomes that are then folded with other proteins to create chromatin, which is DNA in its ...

When the signal arrives in the nucleus, molecules known as chromatin remodeling complexes unfold the condensed DNA in and around the gene and make the region more accessible to the transcriptional ...

The researchers found that this new function involves a new form of activity of 53BP1, in which the protein accumulates at the condensed DNA regions and forms small liquid droplets—a process called ...

Chromosomal regions containing silent genes localize to condensed DNA regions in the outer periphery, whereas active genes stay in the roomier nuclear center, perhaps because there they can more ...