Each eukaryotic chromosome is composed of DNA coiled and condensed around nuclear proteins called histones. Humans inherit one set of chromosomes from their mother and a second set from their father.

Eukaryotic cells, including human cells, form paired condensed chromosomes before cell division. The paired chromosomes are then equally divided into the daughter cells. Prokaryotic cells ...

The model proposes a general mechanism for the formation of condensed mitotic chromosomes, which is applicable to all eukaryotes across a broad range of genome sizes. "We expect that following our ...

A protein complex called condensins is involved in assembling the condensed chromosomes. However, researchers are still unsure how cells achieve chromosome assembly during cell division.

Flemming divided mitosis into two broad parts: a progressive phase, during which the chromosomes condensed and aligned at the center of the spindle, and a regressive phase, during which the sister ...

A protein complex called condensins is involved in assembling the condensed chromosomes. However, researchers are still unsure how cells achieve chromosome assembly during cell division.

In preparation, it tidies up by packing the DNA into dense, sausagelike rods, the chromosomes’ most familiar form. Scientists have watched that process through a microscope for decades: The DNA ...

reveals a highly organized chromosome consisting of two distinct lobes of condensed inactive DNA with smaller structured domains of active DNA embedded in them. These smaller domains, referred to as ...

During cell division, chromosomes begin to condense and remain so until the division is complete. A number of proteins in the cell control the condensation, but so too do free ions such as Mg 2+.

They then generated sophisticated computer simulations to match that data, allowing them to calculate the three-dimensional path the chromosomes traced as they condensed. Their models determined ...