Additionally, we present a complete, descriptive ... Due to their dual activity, the contact-kinin pathway not only triggers thrombus formation by activating intrinsic coagulation via FXI (factor XI) ...

"We look forward to discussing the data with regulators so we can bring this first-in-class alternative complement pathway inhibitor as the first oral monotherapy to people living with PNH," he added.

The role of APC in hyperoxic acute lung injury was tested by studying the physiology of lung injury development, measurement of key coagulation proteins and ... complexes and plasminogen activator ...