This antibody detected phosphorylation of SAS-6::FLAG immunoprecipitated from worm lysates but did not recognize SAS-6(5A)::FLAG immunoprecipitated from lysates of mutant worms carrying phospho-dead ...

Here, we show that a NEver in mitosis Kinase NEKL-3 directly phosphorylates a flexible elbow region between two coiled coil domains connecting the motor head and tail of an intraflagellar transport ...

These actions are induced by hormone binding extracellularly to the ANP receptor 1, thereby activating its intracellular guanylyl cyclase domain for the production of cyclic GMP 2. Here we present ...

Development of a methylation-based, tissue-free test for the detection of molecular residual disease by circulating tumor DNA.

Wag31 has a characteristic N-terminal DivIVA-domain and a C-terminal coiled-coil domain. While the role of Wag31 in polar elongation is known, there is limited mechanistic insight on how it ...

Medicinal Chemistry Research Group, HUN-REN Research Centre for Natural Sciences, Magyar tudósok krt. 2, 1117 Budapest, Hungary National Drug Research and Development Laboratory, HUN-REN Research ...

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Intriguingly, the transcriptional co‐activation function of this protein is critically dependent upon the C‐terminal residues, which constitute a PDZ domain‐binding motif, and is responsible for ...

Motor kinesins are a family of evolutionary conserved proteins involved in intracellular trafficking of various cargoes, first described in the context of axonal transport. They were discovered to ...

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